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Hesperidin an antioxidant found in citrus fruits. It may support circulatory health, boost immune function, promote weight loss, and improve mood. Studies suggest hesperidin may aid in weight management by increasing the metabolic rate. A natural antioxidant and anti-inflammatory, it reduces damage caused by free radicals and may also promote strong bones and healthy skin.
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I read about this supplement in Life Extension magazine which describes how hesperidin and Gynostemma pentaphyllum extract may optimize the activity of AMPK, an enzyme that is activated during times of restricted calorie intake. The reasoning goes that hopefully the use of this herb can prolong life in older animals due to similar effects to that of rapamycine, a drug that induces beneficial autophagy, specifically cleaning out internal fat stores to produce energy. After searching the extract I found this one on Amazon to be the best value. I just started taking the powder along with Gynostemma extract mixing them with bananas or other fruits works fine--the taste is not intolerably bitter as is the case with some other supplements.